Think10

www.Think-10.com is a life science business consultancy, a personal coaching and team development to all businesses and a service to the pharmaceutical industry to facilitate change,

Melanie Lee PhD, CBE, FMedSci, DSc(Hons)

LifeArc

Chief Executive Officer

Principal CEO

BTGplc

BTG plc is a fast growing exciting Interventional Medicine company - on the international stage with it's HQ in London. We have device and drug combination products in the Interventional vascular and oncology space and have recently entered the Interventional Pulmonary area with the acquisition of PneuMRx and their innovative coiled device to treat emphysema patients. Interventional medicine routes to the market place in the hands of skilled physicians is likely to be relevant to many of the emerging new modalities in the pipelines of our innovative biotechs today.

Chief Scientific Officer

NightstaRx Ltd

NightstaRx is a Syncona backed company established to pursue the gene therapy treatment of Choroideremia to prevent the deterioration of eyesight in patients with this X-linked disease which causes loss of sight during the mid 40-50 years of life. Early clinical studies by Robert MacLaren have shown promising efficacy and good safety. The therapy for this indication is to replace the faulty REP1 gene in the eye with a functioning copy in an AAV vector. NightstaRx aims to gain regulatory approval for this therapy with ensuring GMP of the product and agreeing the pivotal clinical path. Www.nightstarx.co.uk

NED (was Founding CEO during 2014)

Syntaxin Ltd

Syntaxin was a successful biotech spun out of the HPA that was developed by myself and my management team, with the help if course of our excellent scientists, to a stage for acquisition to ensure the further investment in the recombinant botulinum toxin technology. Ipsen acquired Syntaxin in July 2013 and the site continues as Ipsen's centre for toxin engineering, complementing well the Ipsen expertise in toxin biology. I left Syntaxin with the acquisition and now work through Think10 as I discuss new opportunities.

Chief Executive officer

EVP and President UCB NewMedicines

Breast Cancer Haven

Angel

Applied Genomics Link Scheme

Working to award funds to innovate collaborative programmes between strong academic groups and small companies.

Chairman

Celltech

EVP R&D, Celltech

Glaxo

Unit Head

I'm a passionate leader dedicated to driving innovation and positive impact in the life sciences industry.🔬

Throughout my career, I have championed the translation of scientific knowledge into impactful healthcare solutions and am passionate about fostering an environment that encourages multidisciplinary collaboration, nurtures scientific talent, and supports the next generation of innovators.

I actively engage with industry leaders, policymakers, and research institutions to shape the future of the life sciences ecosystem.

By participating in conferences, thought leadership activities, and industry forums, I strive to drive positive change and advance the boundaries of medical research.

I am always excited to speak with like-minded professionals, researchers, and individuals passionate about making a difference in healthcare. ⬇️

Let's amplify our impact in healthcare by connecting and collaborating towards a brighter future.🧑🏻‍🔬

Melanie Lee

Krakowska Szkoła Biznesu UEK | Cracow School of Business CUE

MBA 

Clark University

Masters degree

7 years experience in a biotech start-up company. Training and supervision of individuals in molecular biology and protein chemistry techniques. Successfully developed endotoxin low purification methods and established the expression process that delivered the key company drug candidates. Design and implementation of cloning, expression and purification strategies. Development and implementation of assays for the characterization of fusion proteins. 

Completed MPhil while working the full-time at Syntaxin Ltd.

Research Scientist, Lab Supervisor, Events Lead, On-call Rota System Group Leader

Health Protection Agency

Extensive chimera construction. Design of protein purification processes for the target drug candidates produced via the E. coli expression system. Interpretation of biochemical analysis data.

Molecular and Protein Chemistry Scientist, Lab Supervisor

Institute of Biochemistry and Biophysics PAS

Control protein purification using AKTA Prime system that were analyzed by Western blotting and SDS-PAGE. Assisting with radioactive labelled products analysis. Attending lectures and presentations in English.

Student placement during Master of Science (magisterium)

I am a professional senior research and communication specialist. Personally I am delighted to explore the frontiers of research in my projects by innovative thinking and experimentation. I have the ability to stimulate thinking in others by exchange of thoughts and data  to see all sides of an issue and create new ideas. 

I am versatile and proactive. I communicate effectively with stakeholders in diverse parts of business to drive the success of projects.

In terms of skill areas I have worked successfully with a broad number of multidisciplinary assignments which has developed my organisational, communication and leadership qualities. 

These include: 

Organisational: experienced in a start-up biotech company;developing challenging scientific processes; establishing innovative solutions/technologies by evaluating undesired outcomes; organisation and planning of parallel projects; training individuals to high technical competencies; motivating others to drive the goals forward;

Communication: establishing a working relationship and exchanging ideas within collaborations; negotiating cost effective agreements with service providers and collaborators in the scientific sector; raising the cross-communication within company; building trust and understanding issues within diverse groups of people; 

Leadership: team leadership;demonstrating the multi-tasking and cross-functionality (e.g. held five different roles within the company, completed MPhil within 2 years while working at Syntaxin in a full-time position); delegating  tasks to team members, improving the morale of team members;  proactive and independent thinking;

taplio

The Battle

Melanie Lee

Jolanta Tolkacz Coulter

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