Think10

www.Think-10.com is a life science business consultancy, a personal coaching and team development to all businesses and a service to the pharmaceutical industry to facilitate change,

Melanie Lee PhD, CBE, FMedSci, DSc(Hons)

LifeArc

Chief Executive Officer

Principal CEO

BTGplc

BTG plc is a fast growing exciting Interventional Medicine company - on the international stage with it's HQ in London. We have device and drug combination products in the Interventional vascular and oncology space and have recently entered the Interventional Pulmonary area with the acquisition of PneuMRx and their innovative coiled device to treat emphysema patients. Interventional medicine routes to the market place in the hands of skilled physicians is likely to be relevant to many of the emerging new modalities in the pipelines of our innovative biotechs today.

Chief Scientific Officer

NightstaRx Ltd

NightstaRx is a Syncona backed company established to pursue the gene therapy treatment of Choroideremia to prevent the deterioration of eyesight in patients with this X-linked disease which causes loss of sight during the mid 40-50 years of life. Early clinical studies by Robert MacLaren have shown promising efficacy and good safety. The therapy for this indication is to replace the faulty REP1 gene in the eye with a functioning copy in an AAV vector. NightstaRx aims to gain regulatory approval for this therapy with ensuring GMP of the product and agreeing the pivotal clinical path. Www.nightstarx.co.uk

NED (was Founding CEO during 2014)

Syntaxin Ltd

Syntaxin was a successful biotech spun out of the HPA that was developed by myself and my management team, with the help if course of our excellent scientists, to a stage for acquisition to ensure the further investment in the recombinant botulinum toxin technology. Ipsen acquired Syntaxin in July 2013 and the site continues as Ipsen's centre for toxin engineering, complementing well the Ipsen expertise in toxin biology. I left Syntaxin with the acquisition and now work through Think10 as I discuss new opportunities.

Chief Executive officer

EVP and President UCB NewMedicines

Breast Cancer Haven

Angel

Applied Genomics Link Scheme

Working to award funds to innovate collaborative programmes between strong academic groups and small companies.

Chairman

Celltech

EVP R&D, Celltech

Glaxo

Unit Head

I'm a passionate leader dedicated to driving innovation and positive impact in the life sciences industry.🔬

Throughout my career, I have championed the translation of scientific knowledge into impactful healthcare solutions and am passionate about fostering an environment that encourages multidisciplinary collaboration, nurtures scientific talent, and supports the next generation of innovators.

I actively engage with industry leaders, policymakers, and research institutions to shape the future of the life sciences ecosystem.

By participating in conferences, thought leadership activities, and industry forums, I strive to drive positive change and advance the boundaries of medical research.

I am always excited to speak with like-minded professionals, researchers, and individuals passionate about making a difference in healthcare. ⬇️

Let's amplify our impact in healthcare by connecting and collaborating towards a brighter future.🧑🏻‍🔬

Melanie Lee

Single point of accountability and strategic leadership for the development of a medicine from lead optimisation through to end of phase 2 clinical development.

Executive Director, Early Development Leader

Director, Data Strategy and Design. Data and Computational Science.

Director, Data Collaborations

Respiratory External Innovation Director

Head, Cambridge Strategic Partnership

Head, Discovery Process Delivery

Platform Technology & Science Director

GlaxoSmithKline R&D

Director

Therapy area team leader for Metabolic/Musculoskeletal/Proliferative Disorders (2004) & Neurology/Psychiatry (2005, 2006)

Director, Therapy Area Team

Director, Technology Development, Applied Pharmacogenetics

GlaxoSmithKline

Director, Molecular Diagnostics. Pharmacogenetics and Applied Diagnostics

Head Clinical Genotyping

Glaxo Wellcome

Medical University of South Carolina

Faculty position in Molecular Endocrinology

Assistant Professor

A Pharma R&D professional with 28 years business experience. I have worked across the R&D spectrum spanning early target discovery to phase 3 clinical studies. I've led business development and alliance management ventures. I have experience in therapy areas including Immunology, Respiratory, Neuroscience and Oncology. I have extensive matrix and line experience and a passion for helping others develop their careers through coaching and mentoring. 

I am currently an Executive Director, Early Development Lead in the Respiratory & Inflammation Therapy Area; this is a role with sole accountability to deliver a new medicine from lead optimisation to end of phase 2/Proof of Concept. Key strengths required for my role are strategic leadership, executive thinking, decision making, influencing, innovation and agility, stakeholder management at senior R&D board level and superior communication skills.  I am a highly motivated, autonomous self-starter with a ‘can do’ attitude. 

Proven expertise: 
•	Asset Leadership and Delivery. 
-      R&D Strategy and Operations with a focus on delivering results and outcomes.
•	Drug Discovery and Development 
•	Business Development and Alliance Management for relationships spanning academia (UK and US), CROs and technology companies. 
•	Contract negotiation and execution, including IP provisioning 
•	Project and Portfolio Management.
•	Translational / Experimental Medicine.
•	Genetics and genomics.
•	Process improvement change management and risk management.
•	Data handling, processing and reporting for knowledge and information management. 
•	Highly adept at managing complex relationships and negotiating the interfaces with senior stakeholders across R&D, biotech, policy makers and academia.
•	Build trust, maintain confidence, and leverage support to drive significant organizational change.
•	Building and maintaining networks..
•	High learning agility to continually evolve my professional skill set and adapt to change. I am not afraid to take on new roles in new areas. 
•	Skilled in operating at the enterprise level as a leader, team player or individual contributor. 
•	Skilled in communication and stakeholder management across varied audiences – from undergraduates and bench scientists to SVPs, business CEOs, University Deans and Heads of UK Research Councils.
•	Developing capability and talent; high energy level for engaging and motivating people. Accredited Coach.

taplio

The Battle

Melanie Lee

Claire Allan

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